its sequel with Seth Rogen and Zac Efron (and...they're stupid comedies....I don't think you'd like them. She made them watchable for me though.)
I haven't watched Damages, but that's probably her most famous role.
One of her early roles was the 2004 movie Wicker Park with Josh Hartnett, which I even saw in the cinema but didn't know she was in it until last year.
She was fantastic in the AppleTV Series Physical, and she's fun in the other Apple TV series Platonic where she reunites with Rogen.
She shows up in a lot of stuff.
Emma Stone has an Oscar and Jessie Buckley will have other shots, but this is probably Rose Byrne's best chance for one.
Here's her IMDB.